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There are a number of abnormalities associated with the use of propranolol during pregnancy, but many of these may be attributable to underlying diseases. Propranolol should only be given during pregnancy when benefit outweighs risk. Combination of isradipine and propranolol did not significantly affect left ventricular dP/dt max. Significant increases in AUC (27%) and Cmax (58%) and decreases in tmax (23%) of propranolol were noted in this study. If you are or will be breast-feeding while you use Propranolol, check with your doctor.
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